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Animal Models

Monkey Model of Diabetes Mellitus (DM)

  • We provide two kinds of type II diabetic lab-monkey models, one is spontaneous diabetic model, which is screened out from large-scale of farming monkey groups according to the clinical criteria of diabetes mellitus, and the another one is induced diabetic model, which is fed with a special diet from the point of etiology of diabetes, and thus we could obtain a series of diabetic models with different disease processes. Rosiglitazone treatment can effectively improve the symptoms of above monkeys.
  • These models could be applied directly in the pharmacodynamic evaluation of anti-diabetic drugs and etiology research on diabetes.

NHP Model for Parkinson Disease (PD)

  • Among PD animal model, it is said that l-methyl - 4 - phenyl-l, 2, 3, 6 - tetrahydropyridine (MPTP) induced one is comparatively reliable and more close to clinical PD. It is proved as a better PD model by the behavioral and imaging detection, and its conditions can be reversed effectively with the treatment of Madopa.
  • The model can be applied directly in the research on PD drug evaluation.